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This was reported in Taiwan where the implementation of a nationwide hepatitis B vaccination program in 1984 was associated with a decline in the incidence of childhood hepatocellular carcinoma. In countries with high rates of hepatitis B infection, vaccination of newborns has not only reduced the risk of infection, but has also led to a marked reduction in liver cancer. Many countries routinely vaccinate infants against hepatitis B. In the United States vaccination is recommended for nearly all babies at birth. Both versions were developed by Maurice Hilleman and his team. It is on the World Health Organization's List of Essential Medicines. A recombinant version came to market in 1986. The first hepatitis B vaccine was approved in the United States in 1981. They are available both by themselves and in combination with other vaccines. The hepatitis B vaccines are produced with recombinant DNA techniques. It has not been linked to Guillain–Barré syndrome.

It is safe for use during pregnancy or while breastfeeding. Serious side effects from the hepatitis B vaccine are very uncommon. The vaccine is given by injection into a muscle. In those who have been exposed to the hepatitis B virus (HBV) but not immunized, hepatitis B immune globulin should be given in addition to the vaccine. Additional doses may be needed in people with poor immune function but are not necessary for most people. īlood testing to verify that the vaccine has worked is recommended in those at high risk. In healthy people routine immunization results in more than 95% of people being protected. It is also recommended that health-care workers be vaccinated. This includes those with poor immune function such as from HIV/AIDS and those born premature. The first dose is recommended within 24 hours of birth with either two or three more doses given after that. Hepatitis B vaccine is a vaccine that prevents hepatitis B.